Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.8
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Vegetarian capsule
Amount Per Serving
%DV
Bio-Quercetin® Proprietary Blend providing 35% quercetin (10 mg) [from Japanese sophora concentrate flower bud)], 30% galactomannans (8 mg) [from fenugreek (seed)]
30 mg
**
Top Medical Research Studies
9
We recently tested a quercetin-based supplement, Cysta-Q, on 22 patients with interstitial cystitis (IC) in an open-label trial. Over 4 weeks, participants took two capsules daily, and we assessed their symptoms before and after treatment.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
8
We sought to understand how quercetin could alleviate chronic pelvic pain associated with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) using a rat model. Over four weeks, rats received oral quercetin while measuring various blood and prostate health markers.
Our findings revealed that quercetin improved prostate health by reducing inflammation and enhancing antioxidant capacity. Specifically, it lowered levels of harmful inflammatory markers and suppressed certain signaling pathways known to contribute to pain. Overall, quercetin showed significant protective effects against CP/CPPS.
Our findings revealed that quercetin improved prostate health by reducing inflammation and enhancing antioxidant capacity. Specifically, it lowered levels of harmful inflammatory markers and suppressed certain signaling pathways known to contribute to pain. Overall, quercetin showed significant protective effects against CP/CPPS.
7
We investigated how quercetin, a potential treatment for endometriosis-related pelvic pain, affects endometrial stromal cells. By using cells derived from menstrual effluent of both unaffected individuals and those with endometriosis, we observed quercetin's role in promoting decidualization, which is vital for embryo implantation.
Although the study shows promising mechanisms behind quercetin's effects, the direct benefits on reducing pelvic pain require further clinical exploration. Our findings suggest that while quercetin improves cellular responses, additional studies are needed to confirm its effectiveness as a treatment for chronic pelvic pain.
Although the study shows promising mechanisms behind quercetin's effects, the direct benefits on reducing pelvic pain require further clinical exploration. Our findings suggest that while quercetin improves cellular responses, additional studies are needed to confirm its effectiveness as a treatment for chronic pelvic pain.
Most Useful Reviews
9
Eliminated allergy symptoms
1 people found this helpful
I began taking this dietary supplement in spring when my seasonal allergies began acting up. Within a few days, I noticed that there were no traces of allergies - no more tears or a runny nose. During the time I took the supplement, the pelvic pain from an old knee injury also vanished. I no longer need anti-inflammatory or pain relief medications.
7.5
Enhanced immunity noted
Since starting these supplements, I’ve experienced a decrease in my daily pain and inflammation levels. I’ve also noticed stronger immunity against common colds and coughs that my son picks up from school. I will definitely continue taking them!
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.8
- All Researches
9
Quercetin shows promise for endometriosis pain
We explored the effectiveness of a combination treatment involving quercetin, curcumin, and acetylcysteine for easing pelvic pain in women with endometriosis. In this study, 33 women took the supplement daily for two months while we monitored their pain levels related to dysmenorrhea, pelvic pain, and dyspareunia.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
9
Quercetin alleviates pelvic pain
We explored the effects of Phyllanthus niruri extract and its isolated components, including quercetin, on hemorrhagic cystitis induced by cyclophosphamide in mice. The study involved treatment before and after inducing the condition and assessed pain, swelling, and bleeding.
We found that quercetin led to significant pain relief, while other compounds like gallic acid and rutin showed notable anti-inflammatory effects. Overall, the extract and its components proved beneficial in alleviating the treatment's side effects, suggesting potential therapeutic value.
We found that quercetin led to significant pain relief, while other compounds like gallic acid and rutin showed notable anti-inflammatory effects. Overall, the extract and its components proved beneficial in alleviating the treatment's side effects, suggesting potential therapeutic value.
9
We examined the effects of multimodal therapy on chronic pelvic pain using the UPOINT system. After 27 weeks, 100 patients receiving tailored treatments, including quercetin for organ-specific symptoms, showed notable improvement.
About 84% experienced significant symptom reduction, highlighting a median drop in pain scores from 11.5 to 6.1. While quercetin appeared beneficial, there was no guarantee that the number of symptoms predicted the outcome. Overall, this approach signifies a step forward in managing chronic pelvic pain effectively.
About 84% experienced significant symptom reduction, highlighting a median drop in pain scores from 11.5 to 6.1. While quercetin appeared beneficial, there was no guarantee that the number of symptoms predicted the outcome. Overall, this approach signifies a step forward in managing chronic pelvic pain effectively.
9
We recently tested a quercetin-based supplement, Cysta-Q, on 22 patients with interstitial cystitis (IC) in an open-label trial. Over 4 weeks, participants took two capsules daily, and we assessed their symptoms before and after treatment.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
9
We examined the potential of quercetin, a bioflavonoid, in alleviating pelvic pain in men with chronic prostatitis syndromes. In a randomized, double-blind trial involving 30 men, those taking quercetin experienced a notable reduction in symptoms compared to those on a placebo.
Specifically, 67% of men on quercetin showed a 25% improvement in symptoms, compared to just 20% in the placebo group. Even more encouraging, a follow-up with additional participants using a quercetin combination showed an impressive 82% improvement. Overall, quercetin is well tolerated and may significantly help for many facing chronic pelvic pain.
Specifically, 67% of men on quercetin showed a 25% improvement in symptoms, compared to just 20% in the placebo group. Even more encouraging, a follow-up with additional participants using a quercetin combination showed an impressive 82% improvement. Overall, quercetin is well tolerated and may significantly help for many facing chronic pelvic pain.
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Eliminated allergy symptoms
1 people found this helpful
I began taking this dietary supplement in spring when my seasonal allergies began acting up. Within a few days, I noticed that there were no traces of allergies - no more tears or a runny nose. During the time I took the supplement, the pelvic pain from an old knee injury also vanished. I no longer need anti-inflammatory or pain relief medications.
7.5
Enhanced immunity noted
Since starting these supplements, I’ve experienced a decrease in my daily pain and inflammation levels. I’ve also noticed stronger immunity against common colds and coughs that my son picks up from school. I will definitely continue taking them!
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Delenko J, Xue X, Chatterjee PK, Hyman N, Shih AJ, et al. Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosis. Reprod Biol Endocrinol. 2024;22:100. doi:10.1186/s12958-024-01265-z
- Liu H, Wang Z, Xie Q, Chi A, Li Y, et al. Ningmitai capsules have anti-inflammatory and pain-relieving effects in the chronic prostatitis/chronic pelvic pain syndrome mouse model through systemic immunity. Front Pharmacol. 2022;13:949316. doi:10.3389/fphar.2022.949316
- Fadin M, Nicoletti MC, Pellizzato M, Accardi M, Baietti MG, et al. Effectiveness of the integration of quercetin, turmeric, and N-acetylcysteine in reducing inflammation and pain associated with endometriosis. In-vitro and in-vivo studies. Minerva Ginecol. 2020;72:285. doi:10.23736/S0026-4784.20.04615-8
- Krakhotkin DV, Chernylovskyi VA, Bakurov EE, Sperl J. Evaluation of influence of the UPOINT-guided multimodal therapy in men with chronic prostatitis/chronic pelvic pain syndrome on dynamic values NIH-CPSI: a prospective, controlled, comparative study. Ther Adv Urol. 2019;11:1756287219857271. doi:10.1177/1756287219857271
- Maurizi A, De Luca F, Zanghi A, Manzi E, Leonardo C, et al. The role of nutraceutical medications in men with non bacterial chronic prostatitis and chronic pelvic pain syndrome: A prospective non blinded study utilizing flower pollen extracts versus bioflavonoids. Arch Ital Urol Androl. 2019;90:260. doi:10.4081/aiua.2018.4.260
- Park S, Lim W, Bazer FW, Whang KY, Song G. Quercetin inhibits proliferation of endometriosis regulating cyclin D1 and its target microRNAs in vitro and in vivo. J Nutr Biochem. 2019;63:87. doi:10.1016/j.jnutbio.2018.09.024
- Meng LQ, Yang FY, Wang MS, Shi BK, Chen DX, et al. Quercetin protects against chronic prostatitis in rat model through NF-κB and MAPK signaling pathways. Prostate. 2018;78:790. doi:10.1002/pros.23536
- Schiavi MC, Porpora MG, Vena F, Prata G, Sciuga V, et al. Orally Administered Combination of Hyaluronic Acid, Chondroitin Sulfate, Curcumin, and Quercetin in the Prevention of Postcoital Recurrent Urinary Tract Infections: Analysis of 98 Women in Reproductive Age After 6 Months of Treatment. Female Pelvic Med Reconstr Surg. 2019;25:309. doi:10.1097/SPV.0000000000000560
- Güney G, Kaya C, Oto G, Yıldırım S, Özdemir H, et al. Effects of quercetin and surgicel for preventing adhesions after gynecological surgery: A rat uterine horn model. J Obstet Gynaecol Res. 2017;43:179. doi:10.1111/jog.13185
- Boeira VT, Leite CE, Santos AA, Edelweiss MI, Calixto JB, et al. Effects of the hydroalcoholic extract of Phyllanthus niruri and its isolated compounds on cyclophosphamide-induced hemorrhagic cystitis in mouse. Naunyn Schmiedebergs Arch Pharmacol. 2011;384:265. doi:10.1007/s00210-011-0668-0
- Shoskes DA, Nickel JC, Kattan MW. Phenotypically directed multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome: a prospective study using UPOINT. Urology. 2010;75:1249. doi:10.1016/j.urology.2010.01.021
- Shoskes DA, Hakim L, Ghoniem G, Jackson CL. Long-term results of multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome. J Urol. 2003;169:1406.
- Shoskes DA, Albakri Q, Thomas K, Cook D. Cytokine polymorphisms in men with chronic prostatitis/chronic pelvic pain syndrome: association with diagnosis and treatment response. J Urol. 2002;168:331.
- Katske F, Shoskes DA, Sender M, Poliakin R, Gagliano K, et al. Treatment of interstitial cystitis with a quercetin supplement. Tech Urol. 2001;7:44.
- Shoskes DA, Zeitlin SI, Shahed A, Rajfer J. Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial. Urology. 1999;54:960.
